Organic-chemical compound with ice-inhibitory action

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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435219, 435226, 514 19, C12N 948, A61K 3800

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active

057982473

ABSTRACT:
Organic chemical compounds with ICE-inhibitory action which have structures such that they enter into an interaction with binding sites in a binding cavity.

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Journal of Medicinal chemistry, vol. 34, No. 7, Jul. 1991, 1925-1934.
Sleath et al. J. Biol. Chem. vol. 265 No. 24 (Aug. 1990) 14526-28.
Science vol. 256 24 Apr. 1992 p. 441.
Hardtmann et al. J. Med. Chem 1969 12(5) 1093-6 & Abstract.

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