Organic-based porous microspheres for HPLC

Liquid purification or separation – With means to add treating material – Chromatography

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2105021, 210635, 210656, 502402, 502439, 521 56, 521 76, 521188, B01D 1508

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active

049869086

ABSTRACT:
Porous organic microspheres for use in HPLC are formed by coacervating a colloidal silica sol in a uniform mixture of the sol and a polymerizable organic material. The silica particles which formed the sol are removed from the microspheres with ammonium bifluoride. The remaining organic microspheres are rigid, have uniform pore sizes and distribution, and do not swell or shrink in the presence of the solvents used in HPLC.

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