Organic anion transport proteins

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S007200, C435S007800, C435S455000, C435S069100, C436S503000, C424S009200, C424S009600, C530S350000

Reexamination Certificate

active

10736936

ABSTRACT:
The current invention discloses nucleic acid and amino acid sequences for novel organic anion transfer proteins (“OATPs”). The invention encompasses the OATPs described herein, together with vectors containing the cDNA sequences, host cells containing the vectors and polypeptides having all or part of an OATP. Also encompasses are uses for OATPs for targeting drugs to specific organs and for modulating the concentration of endogenous substrates.

REFERENCES:
patent: WO9517905 (1995-07-01), None
patent: WO9731111 (1997-08-01), None
NCBI Entrez Accession No. L19031 (gi:410310), Jacquemin, et al., Mar. 4, 1994.
NCBI Entrez Accession No. P46720 (gi:1171883), Jacquemin, et al., May 1, 2005.
NCBI Entrez Accession No. P46721 (gi:1171882), Kullak-Ublick, et al., May 1, 2005.
NCBI Entrez Accession No. T55488 (gi:657349), Hillier, et al., Feb. 6, 1995.
NCBI Entrez Accession No. U21943 (gi:885977), Kullak-Ublick, et al., Feb. 16, 1996.
NCBI Entrez Accession No. T73863 (gi:690538), Wilson, R.K., Mar. 2, 1995.
NCBI Entrez Accession No. AI027850 (gi:3246549), Strausberg, R., Oct. 30, 1998.
Chen, et al. “Identification of twohERR2-related novel nuclear receptors utilizing bioinformatics and inverse PCR”, Gene, vol. 228, pp. 101-109 (1999).
Hagenbuch, B., et al., Proc. Natl. Acad. Sci. vol. 88, Dec. 1991 pp. 10629-10633.
Hagenbuch,B., et al., The American Society for Clinical Investigation, Inc. vol. 93, Mar. 1994, pp. 1326-1331.
Meier, P.J., et al., Hepatology vol. 26, No. 6, 1997, pp. 1667-1677.
Jacquemin, E., et al., Proc. Natl. Acad. Sci. vol. 91, Jan. 1994, pp. 133-137.
Noe, B.A., et al., Proc. Nat; Acad. Sci. vol. 94, Sep. 1997, pp. 10346-10350.
Abe, T., et al. , J. Biol. Chem. vol. 273, No. 18, (1998), pp. 11395-11401.
Bossuyt, X., et al., J. Pharmacol. Exp. Ther. vol. 276, (1996), pp. 891-896.
Bossuyt, X., et al., J. Hepatol. vol. 25, (1996) pp. 733-738.
Kanai, N., et al., Am. J. Physiol. vol. 270, (1996) pp. F319-F325.
Kanai, N., et al., Am. J. Physiol. vol. 270, (1996), pp. F326-F331.
Kontaxi, M., et al., J. Pharmacol. Exp. Ther. vol. 279, (1996), pp. 1507-1513.
Li, L., et al., J. Biol. Chem. vol. 273, No. 26, (1998), pp. 16184-16191.
Kullak-Ublick, G.A., et al., Gastroenterology vol. 109, No. 4, (1995), pp. 1274-1282.
Kullak-Ublick, G.A., et al., Hepatology vol. 20, No. 2, (1994), pp. 441-416.
Kullak-Ublick, G.A., et al., FEBS Lett., vol. 424, (1998), pp. 173-176.
Wolkoff, A.W., Semin. Liver Dis., vol. 16, No. 2, (1996), pp. 121-127.
Abe, T., et al., J. Biol. Chem., vol. 273, No. 35 (1998), pp. 22395-22401.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Organic anion transport proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Organic anion transport proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Organic anion transport proteins will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3871349

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.