Organ transplant rejection and associated conditions

Details Organ transplant rejection and associated conditions Organ transplant rejection and associated conditions

2006-11-07

2006-11-07

Le, Long V. (Department: 1641)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007200, C435S007910, C435S007920, C436S512000, C436S514000

Reexamination Certificate

active

07132245

ABSTRACT:
The application discloses markers associated with organ transplant rejection and associated conditions, and in particular provides materials and methods for the diagnosis, prognosis or treatment of chronic rejection of transplanted organ such as heart and kidney. Examples of the markers include ribosomal protein L7, β-transducin, 1-TRAF (also known as TANK) or lysyl-tRNA synthetase, or antibodies against these antigens.

REFERENCES:
patent: 2 268 935 (1994-01-01), None
patent: WO 02/10755 (2002-02-01), None
Linke et al. Clin. Experim Immunol. 2001, vol. 126, p. 173-179; Rothe et al. PNAS (1996) vol. 93: 8241-8246.
Wells et al. Biochemistry 29(37): 8509-8517; “The Protein Folding Problem and Tertiary Structure Prediction, Chapter 14: Computational Complexity Protein Structure Prediction, and the Levinthal Paradox” pp. 492-495.
Skolnick and Fetrow (2000) Trends in Biotech 18: 34-39; Smith and Zhang (1997) The challenges of genome sequence annotation or ‘The devil is in the details’.
Brenner (Apr. 1999) “Errors in genome annotation.” Trends in Genetics 15(4): 132-133;).
U.S. Appl. No. 10/343,132, filed May 9, 2003, Marlene Lydia Rose et al.
Seshadri, et al., “Identification of a transcript that is down-regulated in senescent human fibroblasts”, Journal of Biological Chemistry, 268(25): 18474-18480 (1993).
Kaye, Kenneth M., et al., “Tumor necrosis factor receptor associated factor 2 is a mediator of NF-kappa-B activation by latent infection membrane protein 1, the Epstein-Barr virus transforming protein”, PNAS USA, 93(20): 11085-11090 (1996).
Shiba, Kiyotaka, et al., “Human lysyl-tRNA synthetase accepts nucleotide 73 variants and rescuesEscherichia colidouble-defective mutant”, Journal of Biological Chemistry, 272(36): 22809-22816 (1997).
Rothe, Mike, et al., “I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction”, PNAS USA 93(16): 8241-8246 (1996).

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