Orally distintegrating formulation and process for preparing...

Details Orally distintegrating formulation and process for preparing... Orally distintegrating formulation and process for preparing...

2005-04-30

2010-10-19

Weddington, Kevin (Department: 1614)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

Reexamination Certificate

active

07815935

ABSTRACT:
An orally disintegrating formulation and its preparation are provided. The orally disintegrating formulation comprises an effective amount of a pharmaceutically active ingredient and a matrix, wherein the matrix contains an amino acid and pullulan. The orally disintegrating formulation can disintegrate rapidly in oral cavity and be taken without aid of water; Moreover, the formulation has a low hygroscopicity, so that the requirements for storing or producing the formulation is decreased, and the storage life is elongated to facilitate the administration by a patient and the preparation of the protein and vaccine drugs.

REFERENCES:
patent: 5457895 (1995-10-01), Thompson et al.
patent: 2004/0101494 (2004-05-01), Scott et al.
patent: 2006/0188563 (2006-08-01), Sato et al.
patent: 1394607 (2003-02-01), None
patent: 1429618 (2003-07-01), None
patent: 7157431 (1995-06-01), None
patent: 8291051 (1996-11-01), None
patent: 2002012541 (2002-01-01), None
patent: WO-0050013 (2000-08-01), None
The English abstract for JP 2002012541A (2002).
International Search Report for International Application No. PCT/CN2005/000616, dated Sep. 1, 2005.

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