Orally administrable solid dosage form

Details Orally administrable solid dosage form Orally administrable solid dosage form

1999-05-07

2000-04-18

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424465, 514383, 514384, A61K 920, A61K 948, A61K 4700

Patent

active

060512520

ABSTRACT:
An orally administrable solid dosage form containing a compacted ribavirin composition having an advantageously high tap density of at least 0.6 g/mL as well as surprisingly rapid disintegration and dissolution rates and wherein the ribavirin is subsantially free of polymorphic forms of ribavirin is disclosed.

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Botzolakis, et al., "The role of disintegrants in hard-gelatin capsules", J. Pharm. Pharmacol., 1984, 36:77-84.
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Togo, et al., "Chemoprophylaxis and Therapy of Respiratory Viral Infections", J Infect Dis Jun. 1976 133 Suppl:A109-A113.

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