Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1988-01-25
1990-01-09
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424482, 424489, 424497, A61K 928
Patent
active
048927406
ABSTRACT:
An orally administrable pharmaceutical preparation of improved flavoring characteristics composed of a core material containing a drug and a coated layer applied to its surface, said coated layer being composed of a particulate polymeric substance having an average particle diameter of not more than 60 microns and being soluble in gastric juice; and a process for producing said orally administrable pharmaceutical preparation, which comprises causing minute liquid droplets of a volatile liquid containing a drug and optionally a gastric juice-soluble polymeric substance to fall onto a powder bed composed of a gastric juice-soluble particulate polymeric substance having an average particle diameter of not more than 60 microns to coat the surface of the liquid droplets with the gastric juice-soluble particulate polymeric substance, and drying the coated particles.
REFERENCES:
patent: 3202731 (1965-08-01), Grevenstuk et al.
patent: 3968277 (1976-07-01), Takase
patent: 4150110 (1979-04-01), Yoshida et al.
patent: 4443497 (1984-04-01), Samejima et al.
Koyama Ikuo
Maezuru Kaoru
Shimano Kimihide
Takasima Yasuji
Page Thurman K.
Prater P. L.
Taisho Pharmaceutical Co. Ltd.
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