Oral veterinary composition containing a fluoroquinolone antibac

Details Oral veterinary composition containing a fluoroquinolone antibac Oral veterinary composition containing a fluoroquinolone antibac

1998-09-23

2000-10-24

Spear, James M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Specially adapted for ruminant animal

424442, 424451, 424455, 424464, 424466, 424489, 514937, 514944, A61K 908, A61K 910, A61K 914, A61K 920, A61K 948

Patent

active

061363383

ABSTRACT:
The present invention concerns a formulation for an oral veterinary composition containing a fluoroquinolone antimicrobial agent or a pharmaceutically acceptable salt thereof, and a method of treating a microbial infection in a ruminant. The present veterinary composition, when administered orally to a ruminating animal (e.g., a cow or a feedlot calf), allows the fluoroquinolone to be readily and extensively absorbed from the rumen into the circulating blood and provides an unexpectedly extended duration of therapeutic antimicrobial blood level.

REFERENCES:
patent: 4670444 (1987-06-01), Grohe et al.
patent: 5179096 (1993-01-01), Gentilini et al.
patent: 5334589 (1994-08-01), Al-Razzak et al.
patent: 5607942 (1997-03-01), Petersen et al.

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