Oral veterinary composition containing a fluoroquinolone antibac

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

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424464, 424466, 424489, 424457, 424468, A61K 916, A61K 922, A61K 946, A61K 952

Patent

active

06024979&

ABSTRACT:
The present invention concerns a formulation for an oral veterinary composition containing a fluoroquinolone antimicrobial agent or a pharmaceutically acceptable salt thereof, and a method of treating a microbial infection in a ruminant. The present veterinary composition, when administered orally to a ruminating animal (e.g., a cow or a feedlot calf), allows the fluoroquinolone to be readily and extensively absorbed from the rumen into the circulating blood and provides an unexpectedly extended duration of therapeutic antimicrobial blood level.

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Prescott, J. F., Baggot, J. D., Antimicrobial Therapy in Veterinary Medicine, Blackwell Scientific Publications, Boston, pp. 34-35 (1988).
Vancutsem, P. M., Babish, J. G., Schwark, W. S., Cornell Vet., 80(2), 173-186 (1990).

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