Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Anti-idiotypic
Patent
1995-06-06
1997-08-12
Loring, Susan A.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Anti-idiotypic
424492, 424493, 424497, 4241511, 4242631, 424486, 5303872, 5303895, 5303884, A61K 39118, A61K 4748, C07K 1642, C07K 1612
Patent
active
056562713
ABSTRACT:
A genus specific chlamydia oral or injectable vaccine is provided which comprises an anti-idiotype antibody capable of producing in an animal an anti-idiotypic antibody or Fab fragment thereof enclosed in microspheres formed of a pharmacologically acceptable polymer is capable of producing in an animal an anti-anti-idiotypic immune response (serum antibody, secretory antibody or T-cell responsee) which recognizes a glycolipid exoantigen (GLXA) of chlamydia. The oral or injectable vaccine is produced from an idiotypic antibody to GLXA which, in turn, is utilized to produce the anti-idiotypic antibody.
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MacDonald Alex Bruce
Saltzman William Mark
Whittum-Hudson Judith A.
Loring Susan A.
The Johns Hopkins University
University of Massachusetts
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