Oral salmon calcitonin pharmaceutical products

Details Oral salmon calcitonin pharmaceutical products Oral salmon calcitonin pharmaceutical products

1996-03-15

1999-06-15

Knode, Marian C.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424475, 424477, 424480, 424491, 424457, 424459, 424461, 424426, 514 12, A61K 928, A61K 930

Patent

active

059120142

ABSTRACT:
Bioavailability of salmon calcitonin to be administered orally is enhanced by a pharmaceutical composition providing targeted release of the peptide to the intestine, together with an absorption enhancer and a sufficient amount of a pH-lowering agent to lower local intestinal pH. Specific concentrations and classes of these agents are disclosed to account for the particular characteristics of salmon calcitonin.

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Kagatani, et al., Pharmaceutical Research, 13(5):739-743 (1996).

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