Oral rabies immunization of carnivores

Details Oral rabies immunization of carnivores Oral rabies immunization of carnivores

1976-01-23

1977-03-29

Rosen, Sam

Drug, bio-affecting and body treating compositions

Lymphokine

424 84, A61K 3928

Patent

active

040149919

ABSTRACT:
A vaccine and method of protecting wild carnivores and especially foxes from rabies virus which comprises setting out and orally administering an immunizing dose of an attenuated liquid antirabies vaccine, said vaccine being enclosed in a bite-permeable hydrophobic plastic container or sheath and said container being surrounded by an acceptable meat bait for the carnivore such as cured sausage. An elongated shape for both the container and bait is preferred. Acceptable vaccines for utilization include ERA/BHK-21 and PRI virus and a plastic elongated polyethylene tube is preferred for the container holding the attenuated vaccine. An effective amount of a temperature stabilizer for the vaccine may be added for operating temperatures of 27.degree..sup.+C. and these temperature stabilizers are selected from purified casein hydrolysates. The present method operates by bite penetration of the plastic container so that the vaccine is transferred to the buccal mucosa of the carnivore and the present method is effective in the treatment of wild carnivores, especially foxes.

REFERENCES:
patent: 3046192 (1962-07-01), Bilyeu

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