Oral pharmaceutical compositions containing non-steroidal...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

Reexamination Certificate

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C424S451000, C424S457000, C424S458000, C424S464000, C424S468000, C424S471000, C424S472000, C424S490000, C424S493000, C424S494000

Reexamination Certificate

active

06902746

ABSTRACT:
The present invention provides oral pharmaceutical compositions for acetic acid class of non-steroidal anti-inflammatory drug (NSAID), particularly ketorolac. The pharmaceutical composition contains a core, a drug layer (which comprises the drug, a binder, and a disintegrant), a protecting layer, and an enteric coating layer. The oral pharmaceutical compositons are particularly useful for treating patients with moderate to acute pain. The present invention also provides a method for making the pharmaceutical compositions and a method for using the pharmaceutical compositions.

REFERENCES:
patent: 5738874 (1998-04-01), Conte et al.
patent: 5753265 (1998-05-01), Bergstrand et al.
patent: 6306842 (2001-10-01), Lai et al.
patent: 6387410 (2002-05-01), Woolfe et al.
patent: 6391341 (2002-05-01), Mendes et al.
patent: 2003/0069255 (2003-04-01), Plachetka

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