Oral mopidamol preparation

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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424 14, 424 16, 424 19, 424 37, A61K 920, A61K 922, A61K 948

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active

045967059

ABSTRACT:
This invention relates to vehicles for the administration of mopidamol. More specifically, this invention relates to a method of treating cardiovascular disorders, malignancy, or thrombosis in a host in need of such treatment which comprises administering to said host a cardiovascularly, antimetastic, or antithrombotic effective amount of a composition comprised of (i) mopidamol or an acid addition salt thereof and (ii) at least one pharmacologically acceptable acid or acid substance, the total amount of acid from acid addition salt present and acid or acid substance being in a ratio of at least about 1 acid equivalent to 1 mol of mopidamol.

REFERENCES:
patent: 4361546 (1982-11-01), Stricker et al.
patent: 4367217 (1983-01-01), Gruber et al.
patent: 4427648 (1984-01-01), Brickl et al.
patent: 4438091 (1984-03-01), Gruber et al.
patent: 4459279 (1984-07-01), Stricker et al.
White et al., CA. 95 #209646w (1981) of Eur. Pat. Appl. 19586, Nov. 26, 1980, 25 pp.
Slichter CA. 94 #529405 (1981) of Ger. Off. 2,964,736, Aug. 28, 1980, 9 pp.
Jardillier et al., CA. 94 #214617w (1981) of Ger. Off. 2,931,573, Feb. 26, 1981, 9 pp.
Niewiarowski et al., CA. 83 #108254p (1975).
Rifkin et al., CA. 79 #132866c (1973).

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