Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-10-13
1983-04-26
Roberts, Elbert L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
A61K 3156
Patent
active
043812988
ABSTRACT:
A male contraceptive composition is described that may be administered orally. This permits adjusting the dose of the constituents to provide for sperm production inhibition and for normal functioning of secondary sex glands to permit normal sexual activity without fertility. The constituents of the composition are gossypol or derivatives thereof for controlling the sperm production combined with an orally active replacement androgen for counteracting the effect of the gossypol or its derivatives upon secondary sex glands. Ranges of composition and discussions of test results are described together with the method of determining the dose levels needed to achieve the desired result. The composition may be preferably administered as a pill. A maintenance dose level may be utilized after azoospermia sperm levels are achieved.
REFERENCES:
patent: 4094977 (1978-06-01), Seeger et al.
patent: 4098802 (1978-07-01), Van der Vies
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