Oral liquid tolterodine composition

Details Oral liquid tolterodine composition Oral liquid tolterodine composition

2006-09-05

2006-09-05

Low, Christopher S. F. (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S261100, C514S254080

Reexamination Certificate

active

07101888

ABSTRACT:
A pharmaceutical composition in a form of an orally deliverable liquid comprises water having in solution therein a pharmaceutically acceptable water-soluble salt of a tolterodine related compound at a therapeutically effective concentration in the composition. The composition has a pH of about 2 to about 6 and further comprises a sweetening agent and an antimicrobial agent at a concentration that is antimicrobially effective at the pH of the composition. The composition is useful for treating a muscarinic receptor mediated disorder, more particularly overactive bladder, in a subject by orally administering to the subject a therapeutically effective amount of the composition.

REFERENCES:
patent: 5922914 (1999-07-01), Gage et al.
patent: 2003/0060513 (2003-03-01), Americ et al.
patent: 2003/0199582 (2003-10-01), Hawley et al.
Pediatric Pharmacotherapy A Monthy News letter for Health Care Professionals Children's Medical Center at the University of Virginia vol. 2 No. 9 Sep. 1996.

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