Oral immunization with multiple particulate antigen delivery sys

Details Oral immunization with multiple particulate antigen delivery sys Oral immunization with multiple particulate antigen delivery sys

1993-10-05

1997-11-25

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

435 693, 4351723, A61K 3915

Patent

active

056909381

ABSTRACT:
Method of inducing a mucosal and or/systemic immune response in a host, comprising the step of administering to the host an effective amount of a Bluetongue antigen in the form of virus like and/or virus core like particles. Vaccines are also provided.

REFERENCES:
Holmgren, FEMS Microbiology Immunology vol. 89, pp. 1-10, "Mucosal immunity and vaccination", 1991.
French, T.J et al. J. Virol. 64(4): 1530-36, 1990.
Lycke, N. et al. Immunology 59:301-308, 1986.
Boslego, J.W. et al. "Gonorrhea Vaccines" In: Vaccines and Immunotherapy S.J. Gruz Ed., Pergamon Press, 1991.
Ellis, R.W. "New Technologies for Making Vaccines", In: Vaccines, Plotkin & Mortimer Eds., W.B. Saunders Co. 1988.
French, T.J. et al. J. Virol. 64(12):5695-5700, 1990.
Huismans, H et al. Virology 157: 180-188, 1987.

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