Oral immunization by transgenic plants

Details Oral immunization by transgenic plants Oral immunization by transgenic plants

1995-06-01

1997-11-11

Housel, James C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

4241841, 435 691, 435 693, 4351723, 800205, 800220, 800235, 800255, A61K 3902, C12N 1531, C12N 510, A01H 500

Patent

active

056860790

ABSTRACT:
The invention is directed to transgenic plants expressing colonization and/or virulence antigens specified by genes from pathogenic microorganisms. It is also directed to the use of such transgenic plants for oral immunization of humans and other animals to elicit a secretory immune response which inhibits colonization of or invasion by such pathogenic microorganisms through a mucosal surface of humans or other animals.

REFERENCES:
patent: 4888170 (1989-12-01), Curtiss
Moffat AS, Science 268:558-60, 1995 (May 5).
Service RF Science 265:1522-1524, 1994 (Sep. 9).
Dittman RE. Summer 1993 Priorities, pp. 40-42.
Kovgan, A.A., V.M. Zhdanov (1989) "Potential vector for introducing animal virus genes into cells of higher plants" Biotekhnologiya 5(2):148-154, **abstract No. 207160n, Chemical Abstracts 110:225.

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