Oral hyposensitization in the treatment of allergies

Details Oral hyposensitization in the treatment of allergies Oral hyposensitization in the treatment of allergies

1986-12-09

1989-04-18

Rollins, Jr., John W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

514 23, 514826, 514885, A61K 3578, A61K 3170

Patent

active

048226114

ABSTRACT:
A method of treating allergies whereby hyposensitization to allergens to which the patient has been found to be sensitive by skin testing and history is induced by sequentially scheduled oral administration of titrated amounts of allergenic extracts in a liquid vehicle comprising defined proportions of a selected hexose monosaccharide and ethyl alcohol in water.

REFERENCES:
Cooper et al: A Controlled Trial of Oral Hyposensitization in Pollen Asthma and Rhinitis in Children. Clin. Allergy, 14, 541-550 (1984).
Taudorf et al: Oral Administration of Grass Pollen to Hay Fever Patients. Allergy, 40, 321-335 (1985).
Bjorksten, et al: Clinical and Immunological Effects of Oral Immunotherapy with a Standardized Birch Pollen Extract. Allergy, 41, 290-295 (1986).
Moller et al: Oral Immunotherapy of Children with Rhinoconjunctivitis Due to Birch Pollen Allergy. Allergy, 41, 271-279 (1986).

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