Drug – bio-affecting and body treating compositions – Dentifrices – Ferment containing
Patent
1973-06-21
1982-06-15
Shapiro, Lionel M.
Drug, bio-affecting and body treating compositions
Dentifrices
Ferment containing
424 94, 435200, A61K 728, C12N 924
Patent
active
043351018
ABSTRACT:
Enzymes called cariogenanases, elaborated by microorganisms are isolated and characterized as polysaccharases capable of degrading cariogenan, a newly discovered glucan of dental plaque composed of .alpha.-(1.fwdarw.3) and .alpha.-(1.fwdarw.2) linkages. The enzymes are isolable from culture broths of various organisms by protein precipitation methods, and have utility as an anti-dental plaque agent, either as the sole enzymatic agent or in combination with dextranases and/or plaque dispersing proteases.
REFERENCES:
patent: 3562385 (1971-02-01), Block et al.
patent: 3590121 (1971-06-01), Shiff et al.
Nollstadt Karl H.
Stoudt Thomas H.
Mahon Frank M.
Merck & Co. , Inc.
Pfeiffer Hesna J.
Shapiro Lionel M.
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