Drug – bio-affecting and body treating compositions – Dentifrices – Oxygen or chlorine releasing compound containing
Patent
1994-03-11
1995-08-01
Rose, Shep
Drug, bio-affecting and body treating compositions
Dentifrices
Oxygen or chlorine releasing compound containing
424 48, 424 49, 424616, 424618, A61K 720, A61K 3340, A61K 3338, A61K 968
Patent
active
054378583
DESCRIPTION:
BRIEF SUMMARY
This application is a 371 of PCT/EP92/01558 dated Jul. 9, 1992.
This invention is directed to oral hygiene agents, a process for their preparation, and a use.
Hitherto, hydrogen peroxide has been used as bleaching and cleaning agent. The use of hydrogen peroxide for decontaminating and deodorizing water, waste water and exhaust air instead of chlorine dioxide is familiar. For oral disinfection, a 3% hydrogen peroxide solution is suitable.
Use of hydrogen peroxide, particularly in the field of disinfection, gains increasing importance as this substance is considerably more environmentally compatible compared to chlorine-containing disinfectants used so far.
However, usability and storage stability of solutions containing hydrogen peroxide are limited in that hydrogen peroxide, particularly when exposed to heat, light, and in the presence of dust, traces of heavy metals and alkaline substances decomposes more or less rapidly to give water and oxygen. In disinfection or bleaching this is quite a desirable phenomenon since oxygen formed in decomposition has a disinfecting and bleaching effect. When storing such solutions, however, this is disadvantageous since solutions containing hydrogen peroxide decompose after a while and lose their disinfecting effect.
From EP-A-0 325 267, peroxide gels are known which contain from 35 to 95% by weight of polyols and, in addition, a stabilizer and hydrogen peroxide. As stabilizers are mentioned antioxidants or UV-absorbing materials such as butoxylated hydroxyanisole, hydroxytoluene, propyl gallate, or other substituted benzophenones. Although these are said to be toxicologically acceptable, they give rise to problems in part.
From AT-PS 349 640, a toothpaste free of polish is known which substantially consists of an oil-in-water emulsion. Hydrogen peroxide stabilization is effected using urea.
From EP-A-0 288 420, an aqueous hydrogen peroxide gel is known which is gelled with polyoxyethylene/polyoxyproplyene block copolymers and contains polyethylene glycol for moisturizing. The substances utilized therein, in particular Pluronics, are not quite toxicologically safe.
Therefore, it was the technical problem of the invention to provide a stabilized hydrogen peroxide for oral hygiene agents which, on the one hand, permits production of usable and storage-stable oral hygiene agents and, on the other hand, has the familiar advantageous disinfecting effect of hydrogen peroxide.
This technical problem is solved by an oral hygiene agent containing, in addition to common ingredients, a silver colloid-stabilized hydrogen peroxide solution in concentrations of from 0.1 to 10% by weight, preferably from 1 to 3% by weight. Such a stabilized hydrogen peroxide solution is available, for instance, from the company Hungerbach-Chemotechnik GmbH under the designation HUWA-SAN. This solution is stabilized by a silver colloid.
The oral hygiene agent of the invention is prepared by mixing common ingredients with said stabilized hydrogen peroxide solution.
Furthermore, the technical problem of the invention is solved by using a silver colloid-stabilized hydrogen peroxide solution for oral hygiene in concentrations of from 0.1 to 10% by weight, preferably from 1 to 3% by weight.
The silver colloid-stabilized hydrogen peroxide solution may be utilized in a variety of oral hygiene agents including toothpaste, toothpaste for sensitive teeth generally containing soluble potassium and strontium salts or hydroxylapatite, mouth wash, dental powder, and chewing gum for dental care. Furthermore, utilization in oral hygiene agents for artificial teeth such as adhesives, adhesive foams and cleaning agents for artificial teeth is possible. The stabilized hydrogen peroxide solution may also be used as a concentrate or a ready-for-use solution to fill up oral douches.
Despite stabilization, outstanding disinfecting effect is obtained by using the silver colloid-stabilized hydrogen peroxide solution. Thus, the disinfecting effect of a stabilized H.sub.2 O.sub.2 solution (HUWA-SAN) was investigated. Here, it wa
REFERENCES:
patent: 1993686 (1935-03-01), Schulenburg
patent: 2295505 (1942-09-01), Shelton
patent: 3350265 (1967-10-01), Rubenstein et al.
patent: 4476108 (1984-10-01), Kesser et al.
patent: 4559223 (1985-12-01), Fox
patent: 4895721 (1990-01-01), Drucker
patent: 4915955 (1990-04-01), Gomori
patent: 5009898 (1991-04-01), Sakuma et al.
patent: 5084268 (1992-01-01), Thaler
patent: 5104644 (1992-04-01), Douglas
Hoburg Albrecht
Hungerbach Heinz
Struzina Werner
Rose Shep
Ulrike Hungerbach
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