Oral Glutamine to reduce stomatitis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

Reissue Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S563000

Reissue Patent

active

10847810

ABSTRACT:
Glutamine is administered orally at a rate of about 4.5 g/m2per day to treat oropharyngeal mucositis. This is administered to patients that experience or may develop oropharyngeal mucositis, especially those caused by chemotherapy or radiotherapy.

REFERENCES:
patent: 2283817 (1942-05-01), Martin
patent: 2868693 (1959-01-01), Shive
patent: 4849408 (1989-07-01), Sommermeyer et al.
patent: 4857555 (1989-08-01), Smith
patent: 4983595 (1991-01-01), Benjamin et al.
patent: 5039704 (1991-08-01), Smith et al.
patent: 5248697 (1993-09-01), Wilmore
patent: 5366723 (1994-11-01), Tulok
patent: 5397803 (1995-03-01), Smith et al.
patent: 5438042 (1995-08-01), Schmidl et al.
patent: 5438075 (1995-08-01), Skubitz et al.
patent: 5545668 (1996-08-01), Skubitz et al.
patent: 5607975 (1997-03-01), Smith et al.
patent: 5658895 (1997-08-01), Aoi et al.
patent: 5684045 (1997-11-01), Smith et al.
patent: 5726146 (1998-03-01), Almada et al.
patent: 5744166 (1998-04-01), Illum
patent: 5763485 (1998-06-01), Smith et al.
patent: 5792753 (1998-08-01), Falk et al.
patent: 5849335 (1998-12-01), Ballevre et al.
patent: 5891467 (1999-04-01), Willis
patent: 5985850 (1999-11-01), Falk et al.
patent: 2003/0099722 (2003-05-01), Baxter
patent: 2005/0090451 (2005-04-01), Klimberg et al.
patent: 0 238 553 (1986-09-01), None
patent: 0401056 (1990-12-01), None
patent: 0614659 (1994-09-01), None
patent: 0845265 (1998-06-01), None
patent: 0873749 (1998-10-01), None
patent: WO 87/01589 (1987-03-01), None
patent: WO-97/14310 (1997-04-01), None
“Parent Nutrition in Patients Receiving Cancer Chemotherapy” by American College of Physicians, a position paper in 1989 American College Physicians, p. 734.
Alverdy, J C., “Effects of glutamine-supplemented diets on immunology of the gut”,Jpen: Journal of Parenteral&Enteral Nutrition, 14(4 Suppl) (Jul.-Aug. 1990) 109S-113S.
Alverdy, J C., et al., “Parenteral nutrition results in bacterial translocation from the gut and death following chemotherapy”,Journal of Parenteral and Enteral Nutrition 14(1 SUPPL) (1990) p8S.
Anonymous, “Parenteral nutrition in patients receiving cancer chemotherapy”,Annals of Internal Medicine, 110(9) (May 1, 1989) 734-6.
Brown, M G., et al., “Glutamine-enhanced enteral diet improves nitrogen balance without increasing portal ammonia”,British Journal of Surgery, 78(11) (Nov. 1991) 1305-6.
Burke, D J., “Effect of Route of Glutamine Administration on Mortality Following Experimental Enterocolitis”,14th Clinical Congress Abstracts,v Abstract (1991) Col. 14, No. 1, Supplement.
Burke, D J., et al., “Glutamine-supplemented total parenteral nutrition improves gut immune function”,Archives of Surgery, 124(12) (Dec. 1989) 1396-9.
Dechelotte, P, “Absorption and metabolic effects of enterally administered glutamine in humans”,Journal of Physiology, 260(5 Pt 1) (May 1991) G677-82.
Deferrari, G, et al., “Splanchnic exchange of amino acids after amino acid ingestion in patients with chronic renal insufficiency”,American Journal of Clinical Nutrition, 48(1) (Jul. 1988) 72-83.
Evans, M A., “Intestinal fuels: glutamine, short-chain fatty acids, and dietary fiber”,Journal of the American Dietetic Association, 92(10) (Oct. 1992) 1239-46.
Fischer, J E., “Total Parenteral Nutrition, Glutamine, and Tumor Growth”,Jpen: Journal of Parenteral&Enteral Nutrition, 14(4 Suppl) (1990) 86S-88S.
Fong, Y M., et al., “Total parenteral nutrition and bowel rest modify the metabolic response to endotoxin in humans”,Annals of Surgery, 210(4) (Oct. 1989) 449-56; discussion 456-7.
Fox, A D., et al., “Effect of a glutamine-supplemented enteral diet on methotrexate-induced enterocolitis”,Jpen: Journal of Parenteral&Enteral Nutrition, 12(4) (Jul.-Aug. 1988) 325-31.
Fox, A D., et al., “Reduction of the severity of enterocolitis by glutamine supplemented enteral diets”,Surgical Forum, 38(1987) 43-44.
Jacobs, D O., “Combined effects of glutamine and epidermal growth factor on the rat intestine”,Surgery, 104(2) (Aug. 1988) 358-64.
Jacobs, D O., et al., “Disparate Effects Of 5-Fluorouracil On The Ileum And Colon Of Enterally Fed Rats With Protection By Dietary Glutamine”,Surgical Forum, 38(1987) 45-46.
Klimberg, V S., et al., “Oral glutamine accelerates healing of the small intestine and improves outcome after whole abdominal radiation”,Archives of Surgery, 125(8) (Aug. 1990) 1040-5.
Klimberg, V S., et al., “Prophylactic glutamine protects the intestinal mucosa from radiation injury”,Cancer, 66(1) (Jul. 1, 1990) 62-8.
Moore, F A., et al., “TEN versus TPN following major abdominal trauma—reduced septic morbidity”,Journal Article. Randomized Controlled Trial Journal of Trauma-Injury Infection&Critical Care, 29(7) (Jul. 1989) 916-22; discussion 922-3.
O'Dwyer, S T., et al., “5-Fluorouracil toxicity on small intestine but not white blood cells is decreased by glutamine”,Clinical Research, 35(3) (1987) 369A.
Parry-Billings, M , et al., “Dose glutamine contribute to immunosuppression after major burns?”,Lancet, 336(8714) (Sep. 1, 1990) 523-5.
Rombeau, J L., “A review of the effects of glutamine-enriched diets on experimentally induced enterocolitis”,Jpen: Journal of Parenteral&Enteral Nutrition, 14 supplement(1991) 100S-105S.
Shou, J , et al., “Dietary manipulation of methotrexate-induced enterocolitis”,Jpen: Journal of Parenteral&Enteral Nutrition, 15(3) (May-Jun. 1991) 307-12.
Smith, R J., et al., “Glutamine nutrition and requirements”,Jpen: Journal of Parenteral&Enteral Nutrition, 14(4 Suppl) (Jul.-Aug. 1990) 94S-99S.
Souba, W W., et al., “Glutamine nutrition in the management of radiation enteritis”,Jpen: Journal of Parenteral&Enteral Nutrition, 14(4 Suppl) (Jul.-Aug. 1990) 106S-108S.
Souba, W W., et al., “Glutamine nutrition: theoretical considerations and therapeutic impact”,Jpen: Journal of Parenteral&Enteral Nurtition, 14(5 Suppl) (Sep.-Oct. 1990) 237S-243S.
Souba, W W., et al., “Intestinal consumption of intravenously administered fuels”,Jpen: Journal of Parenteral&Enteral Nutrition, 9(1) (Jan.-Feb. 1985) 18-22.
Souba, W W., et al., “Oral glutamine reduces bacterial translocation following abdominal radiation”,Journal of Surgical Research, 48(1) (Jan. 1990) 1-5.
Souba, W W., “The gut as a nitrogen-processing organ in the metabolic response to critical illness”,Nutrition Support Services, 8(1988) 15-22.
Steiger, E , et al., “Effects of nutrition on tumor growth and tolerance to chemotherapy”,Journal of Surgical Research, 18(4) Apr. 1975) 455-66.
Vanderhoof, J A., et al., “Effects of oral supplementation of glutamine on small intestinal mucosal mass following resection”,Journal of the American College of Nutrition, 11(2) (Apr. 1992) 223-7.
Wells, C L., et al., “The effect of dietary glutamine and dietary RNA on ileal flora, ileal histology, and bacterial translocation in mice”,Nutrition, 6(1) (Jan.-Feb. 1990) 70-5; discussion 80-3.
Windmueller, H G., “Glutamine utilization by the small intestine”,Advances in Enzymology&Related Areas of Molecular Biology, 53(1982) 201-37.
Windmueller, H G., et al., “Intestinal metabolism of glutamine and glutamate from the lumen as compared to glutamine from blood”,Archives of Biochemistry&Biophysics, 171(2) (Dec. 1975) 662-72.
Windmueller, H G., et al., “Respiratory fuels and nitrogen metabolism in vivo in small intestine of fed rats. Quantitative importance of glutamine, glutamate, and aspartate”,Journal of Biological Chemistry, 255(1) (Jan. 10, 1980) 107-112.
Ziegler, T R., et al., “Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation. A randomized double-

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Oral Glutamine to reduce stomatitis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Oral Glutamine to reduce stomatitis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oral Glutamine to reduce stomatitis will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3866486

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.