Oral general anesthetics and metabolitically resistant...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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Details

C540S526000, C548S485000, C564S170000, C568S812000

Reexamination Certificate

active

07414078

ABSTRACT:
The present invention is directed to novel themisone derivative compounds that have been modified to prevent the formation of the toxic metabolite, 2-phenyl-acrylamide. Compositions comprising such derivative compounds have activity as anesthetics and as neuroprotective agents.

REFERENCES:
patent: 2005/0228033 (2005-10-01), Brown
patent: 2723464 (1977-12-01), None
CAS Search Printout for Zelenin et al. Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1985, 4, 955-6.
CAS Search Printout for DE2723464A1 is provided.
Zelenin et al. Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya 1986, 9, 2080-5; (CAS Abstract Attached).
Blitz et al. Chem. Lab., Univ. Kiel. Ber. 1908, 41, 1379-93; (CAS Abstract attached).
Page et al. Tetrahedron 1992, 48(35), 7265-74; (CAS Abstract and structures attached).

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