Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2006-08-29
2006-08-29
Ghali, Isis (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
C424S464000, C424S465000, C424S472000, C424S474000, C424S451000
Reexamination Certificate
active
07097851
ABSTRACT:
An oral formulation for gastrointestinal drug delivery which comprises an adhesion site-controlling layer for attaching the formulation to the selected site in the digestive tract, a drug-carrying layer for containing a drug and an adhesive and a protecting layer for protecting the drug in the drug-carrying layer, wherein the drug-carrying layer exists between the protecting layer and the adhesion site-controlling layer, and the adhesion site-controlling layer may attach to the protecting layer. The formulation can improve bioavailability of drugs which have low bioavailability.
REFERENCES:
patent: 4765983 (1988-08-01), Takayanagi et al.
patent: 4767627 (1988-08-01), Caldwell et al.
patent: 5236713 (1993-08-01), Wato et al.
patent: 5350741 (1994-09-01), Takada
patent: 5637319 (1997-06-01), Takada
patent: 5686105 (1997-11-01), Kelm et al.
patent: 5700478 (1997-12-01), Biegajski et al.
patent: 6086869 (2000-07-01), Uyama et al.
patent: 6194000 (2001-02-01), Smith et al.
patent: 6231888 (2001-05-01), Lerner et al.
patent: 98/24412 (1998-06-01), None
“Pharmaceutical Research”, vol. 2, pp. 397-405 (1995).
Takada, “Pharm. Tech. Japan”, pp. 1299-1307 (1988).
Takada, “Pharm. Tech. Japan”, pp. 512-515, 518-521 (1991).
Takada, “Pharm. Tech. Japan”, pp. 1335-1344 (1995).
Ko et al., Nippon Rinsho, “Japan Clinicals”, pp. 595-600 (1998), (with English language abstract).
Ohyama Takao et al., Ishoku [Transplantation], vol. 34, No. 4, pp. 174-185 (1999), (with English language abstract).
Takada, “Pharm. Tech. Japan”, 1995, pp. 903-913.
Takada, “Pharm. Tech Japan”, 1995, pp. 1035-1042.
Oral Protein/Peptide Delivery Technology, Ver 1.2, Mar. 1, 2002, Gastrointestinal Mucoadhesive Patch System (GI-MAPS™), pp. 1-6.
Ghali Isis
Greenblum & Bernstein P.L.C.
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