Oral cyclopsporin formulations

Details Oral cyclopsporin formulations Oral cyclopsporin formulations

1995-08-25

1998-11-10

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

514885, 514962, 514937, 514975, A61K 910, A61K 948

Patent

active

058340173

ABSTRACT:
Improved oral cyclosporin formulations which have high bioavailability and are capable of administration in hard capsules, are provided. In the subject formulations, cyclosporin is delivered in an orally acceptable vehicle comprising at least one alkanol of from 2 to 3 carbon atoms in combination with at least one non-ionic surfactant and an ester of an alcohol and a fatty acid having a hydrocarbon chain of from 14 to 18 carbon atoms. The subject formulations find use in immunosuppressive therapy.

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