Oral compositions of tranexamic acid and carvone

Details Oral compositions of tranexamic acid and carvone Oral compositions of tranexamic acid and carvone

1981-04-02

1984-08-14

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Ammonia, amine, or derivative thereof

424 48, 424 49, 424 58, A61K 716, A61K 722, A61K 726, A61K 968

Patent

active

044656629

ABSTRACT:
An oral composition containing tranexamic acid in which carvone is blended in an amount of 0.1 to 5% by weight and l-menthol may preferably be blended in an amount of 0.03 to 10% by weight. Carvone improves the bitterness inherent to the tranexamic acid-containing oral composition. The composition may preferably contain a mixed humectant of sorbitol and glycerin at a weight ratio of 1:9 to 6:4 and a binder, at least 60% by weight of the binder being an alkali metal salt of carboxymethyl cellulose.

REFERENCES:
patent: 3720762 (1973-03-01), Hatasa
patent: 4272512 (1981-06-01), Gaffar
patent: 4272513 (1981-06-01), Gaffar
patent: 4309410 (1982-01-01), Gaffar
Merck Index, 9th Ed., 1976 #1867.
Merck Index, 9th Ed., 1976 #5663.
Jacobs Am. Perf., 61:469-471, Jun. 1953, Flavoring Mouth Washes.
Jacobs Am. Perf., 61:389, 391, 393, May 1953, How to Flavor Toothpaste.

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