Oral compositions of H2-antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514400, 514471, 424683, 424684, 424687, A61K 31425, A61K 31415, A61K 3134, A61K 3312, A61K 3306, A61K 3308

Patent

active

056229801

ABSTRACT:
The present invention provides a pharmaceutical composition for the oral administration of an H.sub.2 -antagonist. The composition includes an H.sub.2 -antagonist and a silicate taste-masking agent capable of forming an adsorbate complex with the H.sub.2 -antagonist wherein the complex exhibits a non-bitter taste. The complex inhibits the release of the H.sub.2 -antagonist in the oral cavity.

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