Oral compositions for calculus retardation

Drug – bio-affecting and body treating compositions – Dentifrices – Ammonia – amine – or derivative thereof

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A61K 722

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active

041443241

ABSTRACT:
Oral compositions, such as foods, toothpaste, mouthwash, and the like, containing certain polyamine polyphosphonates as herein defined which retard dental calculus formation without damaging tooth structure.

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Monsanto Brochure, Dequest* Organophosphorus Compounds (Feb. 1971)
Briner et al., Calc. Tiss. Res. 7: 249-256 (1971) "Factors Affecting the Rate of Post-Eruptive Maturation of Dental Enamel".
Meyer and Nancollas, Calc. Tiss. Res. 13: 295-303 (1973) The Influence of Multidentate Organic Phosphonates on the Crystal Growth of Hydroxyapatite.

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