Oral compositions for calculus retardation

Drug – bio-affecting and body treating compositions – Dentifrices – Ammonia – amine – or derivative thereof

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A61K 722

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active

041431286

ABSTRACT:
Oral compositions, such as foods, toothpaste, mouthwash, and the like, containing certain polyamine polyphosphonates as herein defined which retard dental calculus formation without damaging tooth structure.

REFERENCES:
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patent: 3288846 (1966-11-01), Irani et al.
patent: 3298956 (1967-01-01), Irani et al.
patent: 3336221 (1967-08-01), Ralston
patent: 3434969 (1969-03-01), Ralston
patent: 3639569 (1972-02-01), Medcalf
patent: 3671644 (1972-06-01), Irani et al.
patent: 3792152 (1974-02-01), Kim
patent: 3832396 (1974-08-01), Irani et al.
Monsanto Co. brochure "Dequest-Organophosphorus Compounds", 3 pp. (shows Dequest 2041 Ethylenediamine Tetra(methylphosphonic acid 2 p.p.m. as water softener).
Briner et al., Calc. Tiss. Res. 7: 249-256 (1971), "Factors Affecting the Rate of Post-Eruptive Maturation of Dental Enamel".
Meyer and Nancollas, Calc. Tiss. Res. 13: 295-303 (1973), "The Influence of Multidentate Organic Phosphonates on the Crystal Growth of Hydroxyapatite".

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