Drug – bio-affecting and body treating compositions – Dentifrices – Hydroxy carboxylic acid or derivative thereof
Patent
1994-06-07
1996-03-19
Killos, Paul J.
Drug, bio-affecting and body treating compositions
Dentifrices
Hydroxy carboxylic acid or derivative thereof
562561, 562575, A61K 724
Patent
active
055002080
ABSTRACT:
The present invention relates to a tripepride having the amino acid sequence Alanine-lsoleucine-Phenylalanine. This invention also relates to methods and compositions for inhibiting growth of dental plaque on tissues within an oral cavity of a human or other animal comprising topical administration, to tissues of such oral cavity, of a composition comprising a safe and effective amount of the tripepride.
REFERENCES:
patent: 4866161 (1989-09-01), Sikes et al.
patent: 5171561 (1992-12-01), Nathoo et al.
CA 84:12741 1975.
CA 98:157700 1982.
Lamberts, B. L., E. D. Pederson and L. G. Simonson, "The Effects of Basic and Acidic Synthetic Polypeptides on the adherence of the Oral Bacterial, Streptococcus mutans and Streptococcus sanguis, to Hydroxyapatite", Archs. Oral Biol., vol. 30, No. 3 (1985), pp. 295-298.
Clark Karen F.
Killos Paul J.
Rasser Jacobus C.
The Procter & Gamble & Company
Zea Betty J.
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