Oral compositions and methods for treating gingivitis

Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing

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424 53, 514859, 514900, 514901, 514902, A61K 716, A61K 718, A61K 968

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active

047160357

ABSTRACT:
This invention relates to oral compositions comprising certain organic peroxy acid antigingivitis agents and a source of F.sup.- fluoride ions as an anticaries agent. Organic peroxy acid-based antigingivitis agents useful in the present invention include monoperphthalic acid and its derivatives, and 1,12-dodecanedioic peroxy acid and its derivatives. Sources of F.sup.- fluoride ions for use in the present invention include sodium fluoride, stannous fluoride, strontium fluoride, indium fluoride, and amine fluorides.
The present invention further relates to methods for treating or preventing diseases of the oral cavity in humans or lower animals with reduced staining of the teeth or dentures. These methods comprise topically applying to the oral surfaces of the human or lower animal a safe and effective amount of a composition of the present invention.

REFERENCES:
patent: 3988433 (1976-10-01), Benedict
patent: 4350681 (1982-09-01), Fulton
patent: 4385008 (1983-05-01), Hignett
patent: 4403994 (1983-09-01), Hignett
patent: 4483781 (1984-11-01), Hartman
patent: 4490269 (1984-12-01), Gallopo
Merka et al., "Disinfectant Properties of Some Peroxide Compounds," Voenno-Med. Zh., vol. 2, pp. 46-50 (1967); Chemical Abstracts 67: 67542e.

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