Oral compositions and methods for reducing dental calculus

Drug – bio-affecting and body treating compositions – Dentifrices – Hydroxy carboxylic acid or derivative thereof

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424 48, 424 49, 424464, 514901, A61K 724

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active

048466506

ABSTRACT:
The present invention relates to oral compositions, such as dentrifices, toothpastes and mounthwashes, which provide an anticalculus benefit. These compositions comprise a safe and effective amount of an anticalculus agent which is a polyepoxysuccinic acid, or its pharmaceutically-acceptable salts, along with a pharmaceutically-acceptable carrier. The present invention also relates to a method for inhibiting or reducing the development of dental calculus by contacting the oral cavity with a safe and effective amount of an anticalculus agent which is a polyepoxysuccinic acid, or its pharmaceutically-acceptable salt.

REFERENCES:
patent: 3429963 (1969-02-01), Shedlovsky
patent: 3776850 (1973-12-01), Pearson
patent: 4304766 (1981-12-01), Chang
patent: 4627977 (1986-12-01), Gaffar
patent: 4654159 (1987-03-01), Bush et al.
patent: 4661341 (1987-11-01), Benedict et al.
Yoshimasa, Chemical Abstracts, 82, 514 (1975) Abst. No. 17648c.
Matsuzawa, Chem. Abst., 82, 170648 (1975), Abst. No. 170648c.

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