Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1997-05-13
1999-11-02
Kulkosky, Peter F.
Drug, bio-affecting and body treating compositions
Dentifrices
A61K 716
Patent
active
059765062
DESCRIPTION:
BRIEF SUMMARY
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to oral compositions for use in the human mouth. More particularly, it relates to oral compositions which contain agglomerates of particulate materials, which agglomerates impart a sensory benefit to the oral compositions which is perceivable upon use of the oral compositions.
The present invention especially relates to oral compositions which contain agglomerated particulate materials which contain at least a particulate dental abrasive cleaning agent, imparting to the oral composition a sensorially-perceivable cleaning benefit.
2. The Related Art
Oral compositions of the above type have already been proposed in the art. Thus, in EP-A-269,966, EP-A-473,171 and GB-A-2,252,042 oral compositions have been described which contain granules which are made from particulate dental abrasive cleaning agents which have been agglomerated with the aid of organic or inorganic binding agents. Upon use of such oral compositions in the mouth, the consumer perceives the presence of these granules, giving him the sensorial perception of a cleaning efficacy, and during brushing of the teeth with these oral compositions the granules are "crushed" by the pressure of the brush, whereby they fall apart into smaller particles which deliver a polishing effect, which the consumer sensorially perceives by a smooth feel of the oral composition and of the teeth. Typical examples of such granules are made of zeolite and colloidal silica, and magnesium alumino metasilicate as the binding agent or ethylcellulose as the binding agent.
In GB-A-2,272,640 oral compositions are described with abrasive particles which are friable under conditions of use of the composition. These particles are made from a particulate dental abrasive cleaning agent such as silica, which is agglomerated without the aid of an inorganic or organic water-insoluble binding agent, but rather by treatment with water and subsequent drying.
Although these prior proposals may lead to oral compositions that can deliver a certain sensory benefit, such benefit is not quite pronounced in several aspects. Furthermore, where mixtures of different materials are agglomerated, this requires the use of an organic or inorganic binding agent, which makes the manufacture of these agglomerates more expensive.
SUMMARY OF THE INVENTION
We have now found, that agglomerates, substantially free from organic and/or inorganic binding agents, having A) a particle size such that the D.sub.10 is equal to or bigger than 50 micrometer and the D.sub.90 is equal to or smaller than 2000 micrometer and having a D.sub.50 ranging from 80 micrometer to 1500 micrometer, said agglomerates being made up from at least two particulate materials, said materials being chemically and/or physically different from each other, whereby at least one particulate material has B) a particle size such that the D.sub.10 is equal to or bigger than 0.1 micrometer and the D.sub.90 is equal to or smaller than 80 micrometer and a D.sub.50 ranging from 4 to 35 micrometer, and C) at least one other particulate material has a particle size such that the D.sub.10 is equal to or bigger than 0.1 micrometer and the D.sub.90 is equal to or smaller than 100 micrometer and a D.sub.50 ranging from 9 to 70 micrometer, when incorporated into an oral composition yield an oral composition which delivers to the consumer a sensorially-perceivable cleaning and polishing benefit upon the use of such oral composition for brushing the teeth.
The D.sub.10 is the particle size of no more than 10% by weight of the total amount of particles; thus, for example, a D.sub.10 of 50 micrometers means that no more than 10% by weight of the total amount of particles may have a particle size of 50 micrometer or less. The D.sub.50 is the particle size, 50% by weight of the total amount of particles is bigger than and 50% by weight of the total amount of particles is smaller than.
The D.sub.90 is the particle size, 90% by weight of the total amount of the particles should be
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Chesebrough-Pond's USA Co.
Honig Milton L.
Kulkosky Peter F.
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