Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing
Patent
1989-05-19
1991-01-29
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Fluorine or fluorine compound containing
424 57, A61K 916, A61K 918
Patent
active
049884999
ABSTRACT:
The invention relates to oral compositions for combating dental caries. The compositions comprise a fluorine-containing anti-caries agent such as sodium fluoride or sodium monofluorophosphate and a particulate hydroxyapatite as abrasive. These ingredients are surprisingly compatible in that there is a reduced loss of available fluoride upon storage.
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The Relationship between Anticaries Activity of Monofluorophosphate Dentifrices and Their Performances in Laboratory Tests, S. A. Duke, G. C. Forward; Caries Res. 19:284-288 (1985).
Improving the Performance of Sodium Monofluorophosphate to Protect Enamel Against Acid, G. C. Forward, M. A. Bell and S. A. Duke; Caries Res. 13: 61-67 (1979).
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Duke C.A. 102:215149r (1985).
Bristow Neil J.
Carter Peter
Coulson Bryony E.
Trevethan Michael A.
Honig Milton L.
Rose Shep K.
Unilever Patent Holdings B.V.
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