Oral composition having mole ratio of tetra (methylene phosphona

Details Oral composition having mole ratio of tetra (methylene phosphona Oral composition having mole ratio of tetra (methylene phosphona

1983-06-08

1984-03-13

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Fluorine or fluorine compound containing

424 49, 424 34, A61K 716, A61K 718, A61K 722

Patent

active

044367210

ABSTRACT:
Anti-caries, anti-calculus oral composition, such as dental cream or gel or mouthwash, containing a diamine tetra (methylene phosphonic acid) salt, such as ethylene diamine tetra (methylene polyphosphonic acid) salt, and alkali metal fluoride, such as sodium fluoride. The mole ratio of the tetra (methylene phosphonate) portion to fluoride is at least 1.4:1, thereby providing optimum anti-caries and anti-calculus effects.

REFERENCES:
patent: 4137303 (1979-01-01), Gaffar et al.
patent: 4143128 (1979-03-01), Kim et al.
patent: 4177258 (1979-12-01), Gaffar et al.
patent: 4183915 (1980-01-01), Gaffar et al.
Chem. Abstr. 80:74327k, (1974) of Ger. Offen. 2224516, (12-06-73) (Counterpart of Henkel & CIE British Patent No. 1,394,034.
Chem. Abstr. 92:135445a, (1980), of U.S. 4,177,258, (12-04-79).
Chem. Abstr. 99:64269w, (1983), Calcif. Tissue Int. 35:362-365, (1983), Effects of Editempa on Dental Calculus and Caries Formation in vivo.

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