Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing
Patent
1980-09-09
1982-06-15
Cacciapaglia, Jr., Frank
Drug, bio-affecting and body treating compositions
Dentifrices
Fluorine or fluorine compound containing
424 48, A61K 718, A61K 968
Patent
active
043351026
ABSTRACT:
An oral composition for caries prophylaxis which comprises a highly soluble stannous compound such as stannous fluoride preferably in an amount of 0.03 to 5% by weight of the composition as stannous tin, a difficultly soluble stannous compound such as stannous pyrophosphate preferably in an amount of 0.05 to 10% by weight of the composition as stannous tin, a phytic acid compound such as sodium phytate preferably in an amount of 0.1 to 20% by weight of the composition, and the pH of the composition being preferably acidic. A portion of the difficultly soluble stannous compound may be in a precipitate form. The oral composition which may be used as dentifrices, prophylactic pastes, dental flosses and the like permits n.sup.2+ ions to exert its effect because the storage stability is high enough to maintain the increased concentration of active dissolved stannous ions in the composition for a prolonged period of time and can render the tooth enamel more resistant to acid attack when applied to teeth.
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Muhler et al., J.A.D.A. 51, 665 (1955).
Hayashi Satoshi
Naganuma Takeshi
Nakashima Syozi
Ochiai Yoshihito
Ozawa Tosiyuki
Cacciapaglia, Jr. Frank
Lion Corporation
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