Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1990-05-21
1992-09-15
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424490, 424493, 424494, 424495, 424496, 424497, 424499, 424500, 424501, A61K 914, A61K 950
Patent
active
051476550
ABSTRACT:
An oral composition which is adapted to be dispersed in an aqueous carrier substantially immediately prior to administration comprises a multiplicity of particles comprising an active substance, the particles being combined with one or more gelling or swelling agents capable of forming a viscous medium around the particles in an aqueous carrier as well as being provided with a masking surface layer when dispersed in the aqueous carrier. This serves to mask uneven surfaces on the particles and prevent them from adhering to oral mucosa when the composition is ingested and thus makes it easier to administer large dosages of an active substance. The masking surface layer is preferably provided by an increased viscosity of the viscous medium in the immediate vicinity of the particles relative to the viscosity of the surrounding aqueous carrier. A ready-to-use composition is prepared by mixing the composition with an aqueous carrier substantially immediately prior to administration of the composition.
REFERENCES:
patent: 2650895 (1953-09-01), Wallenmeyer et al.
patent: 3056728 (1962-10-01), Ohtaki
patent: 3079303 (1963-02-01), Raff et al.
patent: 3445563 (1969-05-01), Clegg et al.
patent: 4221778 (1980-09-01), Raghunatha
patent: 4254100 (1981-03-01), Keller et al.
patent: 4305933 (1981-12-01), Wiczer
patent: 4393076 (1983-07-01), Noda et al.
patent: 4572833 (1986-02-01), Pedersen et al.
patent: 4704268 (1987-11-01), Kifune
patent: 4762702 (1988-08-01), Gergely et al.
patent: 4882169 (1989-11-01), Ventouras
patent: 4886669 (1989-12-01), Ventouras
A/S Alfred Benzon
Page Thurman K.
Spear James M.
LandOfFree
Oral composition containing particles comprising an active subst does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Oral composition containing particles comprising an active subst, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oral composition containing particles comprising an active subst will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-735071