Oral capsule formulation with increased physical stability

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

Reexamination Certificate

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Details

C424S452000

Reexamination Certificate

active

07011846

ABSTRACT:
A formulation for a stabilized capsule for oral administration of a hydrophobic pharmaceutically active agent; comprising a non-aqueous solubilizer selected from 2-pyrrolidone, N-alkylpyrrolidones and combinations thereof; and a capsule stabilizing agent selected from mono-, di- and triglycerides, mono- and di-fatty esters of polyethylene glycol, fatty acids and combinations thereof wherein capsule integrity is maintained for at least 24 hours is disclosed.

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patent: 6174547 (2001-01-01), Dong et al.
patent: 6267985 (2001-07-01), Chen et al.
patent: 2002/0032220 (2002-03-01), Al-Ghazawi et al.
patent: 0 757 911 (1997-02-01), None

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