Oral capsule formulation with increased physical stability

Details Oral capsule formulation with increased physical stability Oral capsule formulation with increased physical stability

2006-03-14

2006-03-14

Tran, S. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

C424S452000

Reexamination Certificate

active

07011846

ABSTRACT:
A formulation for a stabilized capsule for oral administration of a hydrophobic pharmaceutically active agent; comprising a non-aqueous solubilizer selected from 2-pyrrolidone, N-alkylpyrrolidones and combinations thereof; and a capsule stabilizing agent selected from mono-, di- and triglycerides, mono- and di-fatty esters of polyethylene glycol, fatty acids and combinations thereof wherein capsule integrity is maintained for at least 24 hours is disclosed.

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patent: 2002/0032220 (2002-03-01), Al-Ghazawi et al.
patent: 0 757 911 (1997-02-01), None

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