Oral antibacterial compositions and method for the improvement o

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514412, 514413, 514421, 514529, 514531, 514534, 514546, 514561, 514562, 514572, 424 49, 424 55, A61K 3764, A61K 3702, A61K 3143, A61K 3140

Patent

active

053547489

ABSTRACT:
Oral antibacterial compositions contain a penem or carbapenem antibiotic in combination with an absorption improver selected from substances capable of inhibiting the dipeptidase localized on/in epithelial cells of the small intestine, cilastatin, glutathione and N-acetyl-L-cysteine. Gastrointestinal absorption of the penem or carbapenem antibiotic can be improved by orally administering the absorption improver in combination with the antibiotic.

REFERENCES:
patent: 4215124 (1980-07-01), Christensen et al.
patent: 4255330 (1981-03-01), Christensen et al.
patent: 4260618 (1981-04-01), Christensen
patent: 4272437 (1981-06-01), Menard et al.
patent: 4301074 (1981-11-01), Christensen et al.
patent: 4378314 (1983-03-01), Menard et al.
patent: 4386030 (1983-05-01), Christensen et al.
patent: 4406902 (1983-09-01), Ashton et al.
patent: 4539208 (1985-09-01), Kahan et al.
patent: 4616038 (1986-10-01), Kahan et al.
patent: 4668504 (1987-05-01), Kahan et al.
patent: 4739113 (1988-04-01), Ashton et al.
patent: 4880793 (1989-11-01), Kropp et al.
patent: 4925836 (1990-05-01), Kumagai et al.
patent: 4997829 (1991-03-01), Ishiguro et al.
patent: 5061729 (1991-10-01), Kincses et al.
patent: 5061730 (1991-10-01), Uchida et al.
patent: 5100888 (1992-03-01), Nakagawa et al.
patent: 5153188 (1992-10-01), Nakagawa et al.
Analytical Biochemistry, vol. 163, pp. 219-223, 1987, M. J. M. Hitchcock, et al., "Affinity Purification of Renal Dipeptidase Solubilized with Detergent".
Eur. J. Biochem., vol. 160, pp. 521-525, 1986, T. Hirota, et al., "Characterization of Dehydropeptidase I in the Rat Lung".
Journal of Antimicrobial Chemotherapy, vol. 12, Suppl. D. 1-35, pp. 1-35, 1983, F. M. Kahan, et al., "Thienamycin: Development of Imipenem-Cilastatin".
Embase, No. 86057989, T. Usui, et al., "Toxicological Studies of Imipenem/Cilastatin Sodium (I). Acute Toxicity Studies in Mice and Rats", & Japan Chemotherapy , 1985, 33/Suppl. 4, pp. 119-128.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Oral antibacterial compositions and method for the improvement o does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Oral antibacterial compositions and method for the improvement o, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oral antibacterial compositions and method for the improvement o will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1658729

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.