Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai
Patent
1994-01-26
1997-04-22
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
9,10-seco- cyclopentanohydrophenanthrene ring system doai
A61K 3159
Patent
active
056229410
ABSTRACT:
Method of increasing activated vitamin D blood level by administering orally a 1.alpha.-hydroxyprevitamin D. This previtamin D form increases vitamin D blood level without significant risk of hypercalcemia associated with other oral dosing of vitamin D forms. The 1.alpha.-hydroxyprevitamin is compounded into a pharmaceutical composition in combination with a pharmaceutically acceptable excipient.
REFERENCES:
patent: 2216719 (1940-10-01), Boer
patent: 2434015 (1948-01-01), Rosenberg et al.
patent: 4230701 (1980-10-01), Holick et al.
patent: 4335120 (1982-06-01), Holick et al.
patent: 4505906 (1985-03-01), DeLuca et al.
patent: 4539153 (1985-09-01), Vandewalle et al.
patent: 4728643 (1988-03-01), Holick et al.
patent: 5013728 (1991-05-01), Grodberg
Transactions of the Association of American Physicians, vol. XCII, 1979, pp. 54-63, M. F. Holick, S. C. McNeill, J. A. MacLaughlin, S. A. Holick, M. B. Clark and J. T. Potts, Jr., "Physiologic Implications of the Formation of Previtamin D in Skin".
Chemical Abstracts, vol. 110, No. 10, 1989, Columbus, Ohio, Abstract No. 84136v, M. Takahashi, H. Mochizuki, "Enteric-Soluble Capsule Base Composed of Poly(Ethylene Glycol) or Its Substitutes and Cellulose Acetate Phthalate or Hydroxypropyl Methyl Cellulose Phthalate".
Harrison's Principles of Internal Medicine: Part Eleven, "Disorders of Bone & Mineral Metabolism," Chapter 335, E. Brauwald et al., (eds.) McGraw-Hill, New York (1987) pp. 1860-1865.
M. L. Curtin and W. H. Okamura, J. Am. Chem. Soc., vol. 113 (1991) pp. 6958-6966.
Bishop Charles W.
Knutson Joyce C.
Valliere Charles R.
Cintins Marianne M.
Lunar Corporation
Moezie Minna
Welch Teresa J.
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