Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2004-12-01
2008-09-09
Martinell, James (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
Reexamination Certificate
active
07422860
ABSTRACT:
The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.
REFERENCES:
patent: 4493895 (1985-01-01), Colaruotolo et al.
patent: 4499052 (1985-02-01), Fulwyler
patent: 4946778 (1990-08-01), Ladner et al.
patent: 5055408 (1991-10-01), Higo et al.
patent: 5126276 (1992-06-01), Fish et al.
patent: 5139937 (1992-08-01), Inouye et al.
patent: 5223409 (1993-06-01), Ladner et al.
patent: 5360728 (1994-11-01), Prasher
patent: 5541309 (1996-07-01), Prasher
patent: 5578269 (1996-11-01), Yaremko et al.
patent: 5698450 (1997-12-01), Ringrose et al.
patent: 5701012 (1997-12-01), Ho
patent: 5714666 (1998-02-01), Pritchett et al.
patent: 5798441 (1998-08-01), Cormier et al.
patent: 5846708 (1998-12-01), Hollis et al.
patent: 5932795 (1999-08-01), Koutrakis et al.
patent: 5985214 (1999-11-01), Stylli et al.
patent: 6087114 (2000-07-01), Rider
patent: 6103479 (2000-08-01), Taylor
patent: 6228610 (2001-05-01), Flor et al.
patent: 6239453 (2001-05-01), Yamada et al.
patent: 6248542 (2001-06-01), Rider et al.
patent: 6672947 (2004-01-01), Tsao et al.
patent: 6800448 (2004-10-01), Rider et al.
patent: 6872538 (2005-03-01), Dupriez et al.
patent: 2002/0106786 (2002-08-01), Carvalho et al.
patent: 0 301 583 (1989-02-01), None
patent: 0 823 633 (1998-02-01), None
patent: WO 86/07463 (1986-12-01), None
patent: WO 95/23348 (1995-08-01), None
patent: WO 99/30156 (1999-06-01), None
patent: WO 99/58975 (1999-11-01), None
patent: WO 00/02045 (2000-01-01), None
patent: WO 00/02045 (2000-01-01), None
patent: WO 01/36965 (2001-05-01), None
patent: WO 01/36965 (2001-05-01), None
patent: WO 02/066683 (2002-08-01), None
“Introducing BioFlash™, a Rapid Diagnostic System for the Ultra-Sensitive Detection of Pathogens.” Innovative Biosensors, Inc. [online], 2006. [retrieved on Apr. 10, 2007]. Retrieved from the Internet URL: http://www.innovativebiosensors.com/technology—pathogen—detection.html.
Rider, T.H., et al., “A B Cell-Based Sensor for Rapid Identification of Pathogens,”Science, 301(5630):213-215, 2003.
Pancrazio, J.J. et al., “Development and Application of Cell-Based Biosensors,”Annals of Biomedical Engineering, 27(6):697-711, 1999.
Davis, L.S., et al., “The Induction of T Cell Unresponsiveness by Rapidly Modulating CD3,”J. Immunol.142:1084-1094 (1989).
Parikh, V.S., et al., “COOH Terminus of Membrane IgM is Essential For An Antigen-Specific Induction of Some But Not All Early Activation Events In Mature B Cells,”J. Exp. Med., 174:1103-1109 (1991).
Kostov, Y., et al., “All Solid-State GFP Sensor,” Biotechnology and Bioengineering, Including: Symposium Biotechnology In Energy Production and Conservation, John Wiley & Sons. NY, vol. 70(4):473-477 (2000).
Button, D., et al., “Aequorin-expressing Mammalian Cell Lines Used to Report Ca2+Mobilization,”Cell Calcium,14:663-671, 1993.
Chalfie, M., “Green Fluorescent Protein,”Photochemistry and Photobiology, 62(4):651-656, 1995.
Mosier, D.E. “Primary In Vitro Antibody Responses by Purified Murine B Lymphocytes in Serum-Free Defined Medium,”The Journal of Immunology, 127(4):1490-1493, 1981.
Paddle, B.M. “Biosensors for Chemical and Biological Agents of Defence Interest,”Biosensors&Bioelectronics, 11(11):1079-1113, 1996.
Page, D.L., et al., “A Cell-based Immunobiosensor with Engineered Molecular Recognition-Part II: Enzyme Amplification Systems,”Biosensors&Bioelectronics, 12(6):457-466, 1997.
Pizziconi, V.B., et al., “A Cell-based Immunobiosensor with Engineered Molecular Recognition-Part I: Design Feasibility,”Biosensors&Bioelectronics, 12(4):287-299, 1997.
Shimomura, O., et al., “Calcium Binding, Quantum Yield, and Emitting Molecule in Aequorin Bioluminescence,”Nature, 227:1356-1357, 1970.
Shimomura, O., et al., “Light-emitting Properties of Recombinant Semi-Synthetic Aequorins and Recombinant Fluorescein-conjugated Aequorin for Measuring Cellular Calcium,”Cell Calcium, 14:373-378, 1993.
Wilson, H.A., et al., “Crosslinkage of B Lymphocyte Surface Immunoglobulin by Anti-Ig or Antigen Induces Prolonged Oscillation of Intracellular Ionized Calcium,”Journal of Experimental Medicine, 166:601-606, 1987.
Wilson, H.A., et al., “The B Lymphocyte Calcium Response to Anti-Ig Is Diminished by Membrane Immunoglobulin Cross-Linkage to the Fcγ Receptor,”The Journal of Immunology, 138(6):1712-1718, 1987.
Baylor, D.A., “Photoreceptor Signals and Vision,”Investigative Ophthalmology, 28(1):34-49, 1987.
Kombrink, E. and Somssich, I.E., “Defense Responses of Plants to Pathogens,”Advances in Botanical Research, 21:1-34, 1995.
Berry Shaun
Harper James D.
Hennessy Mark
Hogan Kristine E.
Hollis Mark A.
Hamilton Brook Smith & Reynolds P.C.
Martinell James
Massachusetts Institute of Technology
LandOfFree
Optoelectronic detection system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Optoelectronic detection system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Optoelectronic detection system will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3990334