Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical
Reexamination Certificate
2011-01-11
2011-01-11
Zhou, Shubo (Joe) (Department: 1631)
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Biological or biochemical
C435S006120, C702S020000
Reexamination Certificate
active
07869959
ABSTRACT:
The present invention provides methods for optimizing oligonucleotide hybridization probes for use in basic and clinical research. Specifically, the invention involves hybridizing serially diluted genomic sample to the oligonucleotide probes on the array, such that a signal intensity is produced for each of the probes; computationally identifying optimized probes which exhibit signal intensities that correspond to the serial dilutions of genomic sample and are reproducibly strong relative to non-optimized probes.
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Green Roland
Norton Jason
Nuwaysir Emile F.
Nuwaysir Kate
Richmond Todd
Quarles & Brady LLP
Roche Nimblegen, Inc.
Zhou Shubo (Joe)
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