Optimized minizymes and miniribozymes and uses thereof

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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435 6, 435 9131, 4353201, 536 231, 536 232, 536 245, C07H 2104, C07H 2102, C12N 1585, C12N 1511

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active

060048069

ABSTRACT:
This invention is directed to improved catalytic compounds, minizymes and miniribozymes, capable of hybridizing with a target RNA to be cleaved. The minizymes and miniribozymes and compositions of the present invention may be used in vitro or in vivo. They may be used as diagnostic or therapeutic agents.

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