Optimized method for LID biosensor resonance detection

Data processing: measuring – calibrating – or testing – Measurement system – Measured signal processing

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

07979241

ABSTRACT:
An optical interrogation system is described herein that can interrogate a label-independent-detection (LID) biosensor and monitor a biological event on top of the biosensor without suffering from problematical parasitic reflections and/or problematical pixelation effects. In one embodiment, the optical interrogation system is capable of interrogating a biosensor and using a low pass filter algorithm to digitally remove problematic parasitic reflections contained in the spectrum of an optical resonance which makes it easier to determine whether or not a biological event occurred on the biosensor. In another embodiment, the optical interrogation system is capable of interrogating a biosensor and using an oversampling/smoothing algorithm to reduce oscillations in the estimated location of an optical resonance caused by the problematical pixelation effect which makes it easier to determine whether or not a biological event occurred on the biosensor.

REFERENCES:
patent: 4545250 (1985-10-01), Miwa
patent: 4815843 (1989-03-01), Tiefenthaler et al.
patent: 6100975 (2000-08-01), Smith et al.
patent: 6677873 (2004-01-01), Berezin
patent: 7239395 (2007-07-01), Gollier
patent: 2003/0059820 (2003-03-01), Vo-Dinh
patent: 2005/0044519 (2005-02-01), Sengupta et al.
patent: 2005/0264818 (2005-12-01), Gollier
patent: 2006/0017923 (2006-01-01), Ruchti et al.
patent: 2006/0141611 (2006-06-01), Frutos et al.
patent: 2006/0180750 (2006-08-01), Gollier et al.
patent: 1 236 807 (2002-09-01), None
patent: WO 2004/083820 (2004-09-01), None
K. Tiefenthaler et al., “Integrated Optical Switches and Gas Sensors”, Apr. 1984, Optics Letters, vol. 10, No. 4, pp. 137-139.
K. Cattier et al., “Label-free highly sensitive detection of (small) molecules by wavelength interrogation of integrated optical chips”, Sensors and Actuators B, 2003, vol. 91, pp. 241-251.
M. Wiki et al., “Novel integrated optical sensor based on a grating coupler triplet”, Biosensor & Bioelectronics, vol. 13, 1998, pp. 1181-1185.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Optimized method for LID biosensor resonance detection does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Optimized method for LID biosensor resonance detection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Optimized method for LID biosensor resonance detection will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2623152

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.