Optimized human T1R3 nucleic acid molecule

Details Optimized human T1R3 nucleic acid molecule Optimized human T1R3 nucleic acid molecule

2009-11-11

2011-11-29

Bunner, Bridget E (Department: 1647)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

C435S235100, C435S252300, C530S350000, C536S023100, C536S023500

Reexamination Certificate

active

08067236

ABSTRACT:
The present invention relates to a screening system for modulators of GPCRs. Further it relates to recombinant vector systems for the heterologous expression of heterodimeric g-protein coupled receptors (GPCRs) in eukaryotic host cells. Preferably the functional expression of engineered GPCRs for the perception of sweet and L-amino acid taste or more preferably the use of these receptors for the identification of functional ligands is also encompassed.

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