Optimized capacitive sensor for chemical analysis and measuremen

Details Optimized capacitive sensor for chemical analysis and measuremen Optimized capacitive sensor for chemical analysis and measuremen

1987-05-18

1989-04-18

Marcus, Michael S.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Means for analyzing liquid or solid sample

324 61R, 422 69, 422 90, 422 98, 435817, 436528, 436806, G01N 2722

Patent

active

048225665

ABSTRACT:
An apparatus for detecting the presence and/or measuring the concentration of an analyte in the fluid medium is disclosed. The apparatus relies on biospecific binding between a biochemical binding system and the analyte to change the dielectric properties of a capacitive affinity sensor. The biological affinity sensor is optimized by: (1) adjusting the thickness and dielectric properties of a passivation layer to generally match the impedance of the biological binding system; and (2) minimize the double layer capacitance so that bulk capacitance changes associated with the biological binding system are maximized.

REFERENCES:
patent: 4072576 (1978-02-01), Arwin
patent: 4280815 (1981-07-01), Oberhardt et al.
patent: 4444892 (1984-04-01), Malmros
patent: 4490216 (1984-12-01), McConnell
patent: 4562157 (1985-12-01), Lowe et al.
patent: 4571543 (1986-02-01), Raymond et al.

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