Optimized antisense oligonucleotides complementary to DNA methyl

Details Optimized antisense oligonucleotides complementary to DNA methyl Optimized antisense oligonucleotides complementary to DNA methyl

1998-02-03

2000-05-23

Elliott, George C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

435183, 435193, 435325, 435366, 435371, 435375, 536 231, 536 245, A61K 4800, C12N 900, C12N 1585, C12N 1511, C07H 2104

Patent

active

060666250

ABSTRACT:
The invention provides optimized antisense oligonucleotides complementary to the DNA methyltransferase gene or its RNA transcript. The invention further provides methods for using such antisense oligonucleotides as analytical and diagnostic tools, as potentiators of transgenic plant and animal studies and gene therapy approaches, and as potential therapeutic agents.

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