Optimally labeled oligonucleotides

Details Optimally labeled oligonucleotides Optimally labeled oligonucleotides

1997-08-12

2000-04-04

Riley, Jezia

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 6, 435 912, 536 221, 536 231, 536 243, 536 2433, 536 253, 536 2532, C12Q 168, C12P 1934, C07H 1900, C07H 2102

Patent

active

060460385

ABSTRACT:
A method for the preparation of optimally labeled oligonucleotides wherein label-conjugated nucleotide triphosphates are incorporated into a nucleic acid sequence in a defined repetitive manner which allows for the optimal specific detectability of the oligonucleotide. The oligonucleotides of the present invention are useful in the assay of a wide variety of nucleic acid sequences, specifically wherever labeled nucleic acid probes are desired.

REFERENCES:
patent: 5175270 (1992-12-01), Nilsen et al.
patent: 5403708 (1995-04-01), Brennan et al.
patent: 5487973 (1996-01-01), Nilsen et al.
patent: 5652099 (1997-07-01), Conrad
New England Biolabs Catalog, (New England Biolap Inc., Beverly, MA), p. 97, 1993.

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