Imperforate bowl: centrifugal separators – Process
Patent
1991-08-02
1992-12-15
Yasich, Daniel M.
Imperforate bowl: centrifugal separators
Process
364502, 494 7, 494 10, 494 11, G01M 1900, G05B 1304, G06F 1546
Patent
active
051712067
ABSTRACT:
Method and apparatus for controlling the angular velocity of a centrifuge tube containing a solute and a solvent to obtain desirable sedimentation behavior and/or diffusion behavior of the solute within the tube during centrifuge operations. In one embodiment, the angular velocity is maintained at a near-maximum value until just before precipitation of a solute component is reached within the tube. The tube angular velocity is then reduced as a function of time so that critical precipitation is approached but never occurs in the tube as the centrifuge process continues. In other embodiments, the net flux of solute particles into a given volume element of the centrifuge tube, or the ratio of net fluxes of two or more solutes into a predetermined volume elements, is caused to be a prescribed function of time. One application of this method is minimization of the time required to obtain a desired density gradient separation by a centrifuge process.
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Beckman Instruments Inc.
Harder Paul R.
Liu Wen
May William H.
Yasich Daniel M.
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