Optically detectable organophosphonates

Details Optically detectable organophosphonates Optically detectable organophosphonates

2005-09-16

2009-10-13

Shiao, Rei-Tsang (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C558S170000

Reexamination Certificate

active

07601845

ABSTRACT:
The invention relates to compounds having general formula Iin which X represents an optically detectable moiety, n is an integer with 1≦n≦20, R1is an unbranched or branched alkyl group having 1 to 20 carbon atoms, and R2is hydrogen or —CH2—O—R3group, wherein R3has the same meaning as R1. These compounds are useful as inhibitors of lipolytic enzymes and can be used as tools for analysis as well as discrimination of lipolytic enzymes in biological samples.

REFERENCES:
Oskolkova et al. “Fluorescent organophosphonates as inhibitors of microbial lipases” Chemistry and Physics of Lipids 2003, vol. 125, pp. 103-114.

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